1-Acetyl-4-(4-hydroxyphenyl)piperazine

Holiness Pharmaceutical is a trusted and leading pharmaceutical intermediate exporter, supplier and manufacturer of 1-Acetyl-4-(4-hydroxyphenyl)piperazine, an important piperazine-based advanced intermediate used in the synthesis of Ketoconazole API, a widely used antifungal agent. We supply high-purity intermediates to pharmaceutical manufacturers across 40+ international markets, supporting regulated and semi-regulated API production.

Globally, Holiness Pharmaceutical is recognized among reliable Ketoconazole intermediate manufacturers, offering consistent chemical purity, controlled acetylation, and stable phenolic functionality essential for downstream etherification and final API formation. Our expertise in piperazine chemistry and antifungal drug intermediates positions us as a dependable pharmaceutical intermediate exporter from India.

Our advanced intermediate manufacturing facilities operate in strict compliance with international quality standards including:
➡ DCGI, WHO-GMP aligned, and cGMP guidelines,
ensuring validated synthetic routes, batch-to-batch consistency, complete traceability, and comprehensive quality documentation for this Ketoconazole intermediate.

We export 1-Acetyl-4-(4-hydroxyphenyl)piperazine and other high-value pharmaceutical intermediates from India to Asia, Africa, Europe, the Middle East, North America, South America, and CIS regions, supporting API manufacturers focused on antifungal and dermatological therapies.

Holiness Pharmaceutical is one of the leading producers of advanced pharmaceutical intermediates, delivering reliable supply, scalable production, and globally accepted quality systems as a certified pharmaceutical intermediate supplier and exporter.

Holiness Pharmaceutical Ltd. is a fully integrated organization engaged in the complete lifecycle of intermediates — including route scouting, piperazine synthesis, acetylation chemistry, process optimization, commercial-scale manufacturing, and global supply of advanced intermediates for regulated APIs.

Recognized globally for technical reliability and consistent quality, Holiness Pharmaceutical is positioned among the top pharmaceutical intermediate manufacturers in India, supported by experienced R&D teams, modern manufacturing infrastructure, and a rapidly expanding international customer base.

Holiness Pharmaceutical has established a strong presence in many countries including:
United States, Canada, United Kingdom, Germany, France, Netherlands, Italy, Spain, Australia, New Zealand, Slovakia, Estonia, Belarus, Ukraine, Iceland, Kazakhstan, Uzbekistan, Turkmenistan, Tajikistan, Kyrgyzstan, Georgia, Russia, Yemen, Saudi Arabia, UAE, Qatar, Kuwait, Oman, Bahrain, Turkey, Senegal, Ethiopia, Eswatini, Cameroon, Zambia, Mozambique, Angola, Zimbabwe, Malawi, Seychelles, South Africa, Nigeria, Kenya, Tanzania, Ghana, Egypt, Panama, Costa Rica, El Salvador, Mexico, Brazil, Argentina, Chile, Peru, Colombia, Afghanistan, Bhutan, Cambodia, Vietnam, Indonesia, Philippines, Malaysia, Thailand, South Korea, Japan, Paraguay, Bangladesh.