Anthelmintic APIs
Life-Saving Active Pharmaceutical Ingredients for Parasitic Infection Control
About Anthelmintic APIs
Holiness Pharmaceutical is a leading manufacturer and exporter of high-quality Anthelmintic APIs used in treating parasitic worm infections in both human and veterinary medicine. Our comprehensive portfolio includes benzimidazoles, avermectins, and other antiparasitic agents manufactured under WHO-GMP standards. We support global public health initiatives by ensuring access to effective deworming medications, particularly in endemic regions.
Key Features
- WHO-GMP certified antiparasitic manufacturing facility
- Compliance with IP, BP, USP, and veterinary pharmacopeial standards
- Broad-spectrum anthelmintic agents
- Advanced synthesis and purification technology
- Both human and veterinary pharmaceutical grades
- Comprehensive impurity profiling and control
- Complete regulatory documentation and DMF support
- Support for mass drug administration programs
Application Areas
Intestinal Helminth Infections
Treatment of roundworms, hookworms, whipworms, and other intestinal parasites
Tissue Helminth Infections
Management of neurocysticercosis, hydatid disease, and tissue-dwelling parasites
Onchocerciasis Control
Prevention and treatment of river blindness in endemic regions
Veterinary Deworming
Parasite control in livestock, companion animals, and agricultural applications
Mass Drug Administration
Public health programs for helminth control in endemic populations
Quality Assurance
Our anthelmintic APIs undergo rigorous quality testing including HPLC analysis for purity and related substances, polymorphic form characterization, residual solvent analysis, heavy metal testing, particle size analysis for suspensions, and comprehensive microbiological evaluation. We conduct stability studies under tropical conditions (Zone IV) relevant to endemic regions where these medicines are most needed.
Our Anthelmintic APIs Products
| Product Name | CAS Number | Grade | Form | Actions |
|---|---|---|---|---|
Albendazole API | 54965-21-8 | BP/USP | API Powder | View Product |
Clorsulon API | 60200-06-08 | - | API Powder | View Product |
Closantel Base API | 57808-65-8 | - | API Powder | View Product |
Closantel Sodium API | 61438-64-0 | - | API Powder | View Product |
Ivermectin API | 70288-86-7 | BP/USP | API Powder | View Product |
Mebendazole API | 31431-39-7 | BP/USP | API Powder | View Product |
Niclosamide API | 50-65-7 | BP/USP | API Powder | View Product |
Nitazoxanide API | 55981-09-04 | BP/USP | API Powder | View Product |
Praziquantel API | 55268-74-1 | BP/USP | API Powder | View Product |
Pyrantel Pamoate API | 22204-24-6 | BP/USP | API Powder | View Product |
Frequently Asked Questions
What are Anthelmintic APIs?
Anthelmintic APIs are active pharmaceutical ingredients that treat parasitic worm (helminth) infections. They include benzimidazoles (albendazole, mebendazole) that inhibit parasite microtubule formation, and avermectins (ivermectin) that paralyze and kill parasites. These are essential for treating soil-transmitted helminths and other parasitic diseases.
Which anthelmintic APIs does Holiness Pharmaceutical manufacture?
We manufacture Albendazole, Mebendazole, Ivermectin, Praziquantel, Niclosamide, Nitazoxanide, Pyrantel Pamoate, Triclabendazole, and veterinary-specific products including Closantel and Clorsulon. All products meet BP, USP, or specific veterinary pharmacopeial standards.
What is the difference between Albendazole and Mebendazole?
Both are benzimidazole anthelmintics with similar mechanisms. Albendazole has better oral absorption and tissue penetration, making it effective against both intestinal and tissue parasites including neurocysticercosis. Mebendazole has lower systemic absorption, making it safer for intestinal helminths with minimal systemic effects. Choice depends on infection type and location.
Do you manufacture veterinary-grade anthelmintic APIs?
Yes, we manufacture both human and veterinary pharmaceutical grades. Veterinary products include Ivermectin, Closantel (Sodium and Base), Clorsulon, and others used in livestock, poultry, and companion animals. These meet veterinary pharmacopeial specifications and support animal health and food safety programs worldwide.
How do you ensure stability in tropical climates for anthelmintics?
We conduct stability studies under ICH Zone IVb conditions (30°C/75% RH) representing tropical environments where parasitic infections are endemic. Products are packaged in moisture-barrier materials with proper sealing, and we provide stability data supporting shelf life in challenging climatic conditions. This ensures product quality in regions that need these medicines most.
Can you provide specifications for pediatric chewable formulations?
Yes, we provide APIs suitable for pediatric formulations including appropriate particle size for chewable tablets, compatibility with flavoring agents, and specifications for suspension formulations. Many helminth infections affect children, so we ensure our APIs support development of child-friendly, palatable dosage forms that improve treatment compliance.
Do you support mass drug administration (MDA) programs?
Yes, we actively support WHO-led mass drug administration programs for helminth control. We provide cost-effective, quality-assured APIs, maintain stable supply chains for large-volume requirements, and offer flexible ordering for public health initiatives. We're committed to supporting global efforts to reduce parasitic disease burden.
What is the role of Ivermectin in onchocerciasis control?
Ivermectin is the cornerstone of onchocerciasis (river blindness) elimination programs. It kills microfilariae of Onchocerca volvulus, preventing disease transmission and progression. WHO recommends annual or biannual community-directed treatment with ivermectin in endemic areas. Our Ivermectin API supports these critical public health programs in Africa and Latin America.